Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH)
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چکیده
منابع مشابه
Immune Mechanisms in Non-alcoholic Steatohepatitis (NASH)
Non-alcoholic fatty liver had been believed to be a non-progressive benign disease. However, Ludwig et al. described some patients who exhibited progressive steatohepatitis without habitual alcohol drinking (Ludwig et al., 1980) and referred to this disease as non-alcoholic steatohepatitis (NASH). Later, NASH and non-progressive simple steatosis patients were included in the single disease enti...
متن کاملNon-Alcoholic Steatohepatitis (NASH): Risk Factors in Morbidly Obese Patients
The aim was to investigate the prevalence of non-alcoholic steatohepatitis (NASH) and risk factors for hepatic fibrosis in morbidly obese patients submitted to bariatric surgery. This retrospective study recruited all patients submitted to bariatric surgery from January 2007 to December 2012 at a reference attendance center of Southern Brazil. Clinical and biochemical data were studied as a fun...
متن کاملNutritional aspects in patients with non-alcoholic steatohepatitis (NASH).
BACKGROUND AND OBJECTIVES Metabolic alterations are a common feature in patients affected by non-alcoholic steato-hepatitis (NASH). A strong correlation exists between overweight, in particular visceral fat accumulation, and prevalence of NASH, especially in men. Thus, diet-induced weight loss represents a fundamental tool in disease management of these patients. The aim of the present study wa...
متن کاملNon-alcoholic steatohepatitis (NASH) – is it a part of the metabolic syndrome?
Metabolic syndrome is one of the most frequent diseases of our age, and it is accompanied by numerous complications. Clinical studies have been published suggesting that, in addition to the already well-known consequences of the metabolic syndrome, hepatic involvement should also be taken into consideration in a significant part of cases. Fatty liver or in most cases the histological picture of...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0226854